Bulk Anti-Human CD20 (2H7) Antibody
Product Sizes
1 mg
£131.00
ICH1012-1MG
5 mg
£332.00
ICH1012-5MG
25 mg
£1057.00
ICH1012-25MG
50 mg
£1675.00
ICH1012-50MG
100 mg
£2351.00
ICH1012-100MG
About this Product
- SKU:
- ICH1012
- Additional Names:
- B-lymphocyte surface antigen B1, Bp35, Leukocyte surface antigen Leu-16, Membrane-spanning 4-domains subfamily A member 1, MS4A1
- Application:
- Flow Cytometry, IHC-Frozen, Immunoprecipitation, Mass Cytometry
- CE/IVD:
- RUO
- translate.label.attr.clone:
- 2H7
- Clonality:
- Monoclonal
- Concentration:
- 1-5 mg/ml
- Extra Details:
- The CD20 antigen, also called MS4A1, B1 and Bp35, is a non-glycosylated, transmembrane spanning, phosphoprotein. The CD20 protein is present on human pre B lymphocytes and on B lymphocytes at all stages of maturation, except on plasma cells, and is synchronous with the expression of surface IgM. It is also expressed in some follicular dendritic cells and at low levels on a T cell subset. CD20 has been shown to be heavily phosphorylated in activated B cells and malignant B cells. Homo-oligomeric complexes of CD20 are thought to form Ca2+ conductive ion channels in the plasma membrane of B cells. The CD20 molecule is involved in B cell activation and is associated with various Src family kinases (Lyn, Lck, Fyn), and exists in a complex with MHC class I and II, CD53, CD81, and CD82. Extensive CD20 cross-linking may also influence cell death by apoptosis. Therapy with antibodies against CD20 is a widely used regimen in the treatment of all B cell lymphomas and leukemias.
- Formulation:
- 0.01 M phosphate buffered saline (PBS) pH 7.2, 150 mM NaCl with no carrier protein, potassium or preservatives added.
- Host:
- Mouse
- Immunogen:
- CD20
- Isotype:
- IgG2b, kappa
- Purity:
- >95%
- Purification:
- This monoclonal antibody was purified using Protein A
- Reactivities:
- Human
- Shipping Conditions:
- Blue Ice
- Specificity:
- Anti-CD20 In Vivo Antibody - Low Endotoxin (2H7) recognizes an epitope on Human CD20
- Storage Conditions:
- 2-8[o]C Aliquot. Avoid freeze/thaw cycles., -70[o]C Aliquot. Avoid freeze/thaw cycles.
- Supplier:
- ichorbio
- Type:
- Antibody: Monoclonal Antibody
- Shipping Costs:
- Free shipping to UK Customers
- Main Competition:
- This product is an equivalent to the major product in the market
- Manufacturer's Data Sheet:https://ichor.bio/productpdf/print/index/url_key/Anti-CD20-In-Vivo-Antibody-Low-Endotoxin-2H7-ICH1012/
