Pig Fc gamma RIIa / CD32b protein
Product Sizes
250 ug
£750.00
PIGR2B-U-250UG
5 x 250 ug
£3000.00
PIGR2B-U-5X250UG
About this Product
- SKU:
- PIGR2B-U
- Additional Names:
- CD32, CD32B, FCGR2, FCGR2B, FCGRII, FCGRIIB, FCR2, FCR2B, FCRII, FCRIIB, IGFR2, IGFR2B, IGFRII, IGFRIIB, Fc gamma R2, Fc gamma R2b, Fc gamma RII, Fc gamma RIIb, Fcg R2, Fcg R2b, Fcg RII, Fcg RIIb
- Application:
- Assay Development, ELISA, Immunoassay, Surface Plasmon Resonance
- Extra Details:
- Low affinity immunoglobulin gamma Fc receptor IIb, also known as FcγRIIb or CD32b, is a type I integral membrane glycoprotein. CD32b is a member of the immunoglobulin superfamily and is expressed on B cells, subsets of monocytes, macrophages and granulocytes, platelets and mast cells. CD32b binds monomeric IgG with low affinity but is efficient at binding immune complexes and is a negative regulator of cell activation, proliferation, endocytosis, phagocytosis, and degranulation. CD32b is structurally composed of two extracellular immunoglobulin domains of the C2-type that interact with the IgG Fc domain, a transmembrane domain and a short cytoplasmic tail containing the immunoreceptor tyrosine-based inhibition (ITIM) motif. The product provided only contains the extracellular portion of CD32.
- Shipping Conditions:
- Ambient
- Storage Conditions:
- Lyophilized proteins are stable at ambient temperature for at least 2 weeks. If the protein is not to be used immediately then the protein should be stored in lyophilized form at -20 °C for up 12 months. Once the protein has been reconstituted we recommend storage at 4 °C for up to one week. For longer term storage of protein in solution we recommend aliquoting into smaller vials to avoid repeated freeze-thaw cycles and storage at -20 or -80 °C for up to 3 months. To avoid surface adsorption loss and inactivation we strongly recommend that the protein should not be aliquoted in less than 10 μg per vial.
- Supplier:
- Gamma Proteins
- Type:
- Proteins, Peptides, Small Molecules & Other Biomolecules: Recombinant Proteins
