Pig Fc gamma RI / CD64 protein
Product Sizes
250 ug
£750.00
PIGR1-U-250UG
5 x 250 ug
£3000.00
PIGR1-U-5X250UG
About this Product
- SKU:
- PIGR1-U
- Additional Names:
- CD64, CD64A, FCGR1, FCGRI, FCGR1A, FCGRIA, FCR1, FCRI, IGFR1, IGFRI, Fc gamma R1, Fc gamma RI, Fcg R1, Fcg RI
- Application:
- Assay Development, ELISA, Immunoassay, Surface Plasmon Resonance
- Extra Details:
- High affinity immunoglobulin gamma Fc receptor I, also known as FcγRI or CD64, is a type I integral membrane glycoprotein. CD64 is a member of the immunoglobulin superfamily and is expressed on monocytes, macrophages, dendritic cells and activated granulocytes. CD64 binds with high affinity to the Fc domain of IgG and it plays a role in antigen capture, phagocytosis of IgG/antigen complexes, and antibody-dependent cellular cytotoxicity (ADCC). CD64 is structurally composed of three extracellular immunoglobulin domains of the C2-type that interact with the IgG Fc domain, a transmembrane domain and a short cytoplasmic tail. CD64 is associated with a dimer of the common Fc receptor gamma-chain which contains the immunoreceptor tyrosine-based activation (ITAM) motif. The product provided only contains the extracellular portion of CD64.
- Shipping Conditions:
- Ambient
- Storage Conditions:
- Lyophilized proteins are stable at ambient temperature for at least 2 weeks. If the protein is not to be used immediately then the protein should be stored in lyophilized form at -20 °C for up 12 months. Once the protein has been reconstituted we recommend storage at 4 °C for up to one week. For longer term storage of protein in solution we recommend aliquoting into smaller vials to avoid repeated freeze-thaw cycles and storage at -20 or -80 °C for up to 3 months. To avoid surface adsorption loss and inactivation we strongly recommend that the protein should not be aliquoted in less than 10 μg per vial.
- Supplier:
- Gamma Proteins
- Type:
- Proteins, Peptides, Small Molecules & Other Biomolecules: Recombinant Proteins
