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Proteins and Peptides

Marmoset Fc gamma RIIIa / CD16a protein

Product Sizes
500 ug
£750.00
MAGR3A-500UG
5 x 500 ug
£3000.00
MAGR3A-5X500UG
About this Product
SKU:
MAGR3A
Additional Names:
CD16, CD16A, FCGR3, FCGR3A, FCGRIII, FCGRIIIA, FCR3, FCR3A, FCRIII, FCRIIIA, IGFR3, IGFR3A, IGFRIII, IGFRIIIA, Fc gamma R3, Fc gamma R3a, Fc gamma RIII, Fc gamma RIIIa, Fcg R3, Fcg R3a, Fcg RIII, Fcg RIIIa
Application:
Assay Development, ELISA, Immunoassay, Surface Plasmon Resonance
Extra Details:
Low affinity immunoglobulin gamma Fc receptor IIIa, also known as FcγRIIIa or CD16a, is a type I integral membrane glycoprotein. CD16a is a member of the immunoglobulin superfamily and is expressed on macrophages, monocytes and NK cells. CD16a binds monomeric IgG with low affinity but is efficient at binding immune complexes and functions in NK cell activation, phagocytosis and antibody-dependent cellular cytotoxicity (ADCC). CD16a is structurally composed of two extracellular immunoglobulin domains of the C2-type that interact with the IgG Fc domain, a transmembrane domain and a short cytoplasmic tail. CD16a is associated with a dimer of the common Fc receptor gamma-chain which contains the immunoreceptor tyrosine-based activation (ITAM) motif. The product provided only contains the extracellular portion of CD16a.
Formulation:
Lyophilized from sterile PBS, pH 7.4. No preservatives or cryoprotectants have been added.
Purity:
>95% monomer purity as determined by SDS-PAGE and SEC-HPLC.
Shipping Conditions:
Ambient
Storage Conditions:
See datasheet for more information
Supplier:
Gamma Proteins
Type:
Proteins, Peptides, Small Molecules & Other Biomolecules: Recombinant Proteins