Marmoset Fc gamma RIIb / CD32b protein
Product Sizes
500 ug
£750.00
MAGR2B-500UG
5 x 500 ug
£3000.00
MAGR2B-5X500UG
About this Product
- SKU:
- MAGR2B
- Additional Names:
- CD32, CD32B, FCGR2, FCGR2B, FCGRII, FCGRIIB, FCR2, FCR2B, FCRII, FCRIIB, IGFR2, IGFR2B, IGFRII, IGFRIIB, Fc gamma R2, Fc gamma R2b, Fc gamma RII, Fc gamma RIIb, Fcg R2, Fcg R2b, Fcg RII, Fcg RIIb
- Application:
- Assay Development, ELISA, Immunoassay, Surface Plasmon Resonance
- Extra Details:
- Low affinity immunoglobulin gamma Fc receptor IIb, also known as FcγRIIb or CD32b, is a type I integral membrane glycoprotein. CD32b is a member of the immunoglobulin superfamily and is expressed on B cells, subsets of monocytes, macrophages and granulocytes, platelets and mast cells. CD32b binds monomeric IgG with low affinity but is efficient at binding immune complexes and is a negative regulator of cell activation, proliferation, endocytosis, phagocytosis, and degranulation. CD32b is structurally composed of two extracellular immunoglobulin domains of the C2-type that interact with the IgG Fc domain, a transmembrane domain and a short cytoplasmic tail containing the immunoreceptor tyrosine-based inhibition (ITIM) motif. The product provided only contains the extracellular portion of CD32.
- Formulation:
- Lyophilized from sterile PBS, pH 7.4. No preservatives or cryoprotectants have been added.
- Purity:
- >95% monomer purity as determined by SDS-PAGE and SEC-HPLC.
- Shipping Conditions:
- Ambient
- Storage Conditions:
- See datasheet for more information
- Supplier:
- Gamma Proteins
- Type:
- Proteins, Peptides, Small Molecules & Other Biomolecules: Recombinant Proteins
