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Product Sizes
5 mg
£187.00
10-5887-5MG
25 mg
£310.00
10-5887-25MG
About this Product
SKU:
10-5887
CAS Number:
30195-30-3
Extra Details:
Ro 5-3335 was identified in a screen for inhibitors of the RUNX1-CBFB Beta interaction. It represses RUNX1/CBFB-dependent transactivation in reporter assays and runx1-dependent hematopoiesis in zebrafish embryos.1 Ro 5-3335 slows disease progression in various models including acute kidney injury2, acute myocardial infarction3 and osteoarthritis4 among others5. It synergizes with an HDAC inhibitor enhancing the activation of latent HIV-1 in both cell lines and patient PBMCs.6
Immunogen:
Transcription factor
Molecular Weight:
259.69
Physical State:
Solid
Purity:
>98%
Shipping Conditions:
Ambient
Storage Conditions:
-20[o]C
Supplier:
Focus Biomolecules
Type:
Proteins, Peptides, Small Molecules & Other Biomolecules: Inhibitors