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Proteins and Peptides

Lactoyl phenylalanine

Product Sizes
5 mg
£173.00
10-5713-5MG
25 mg
£339.00
10-5713-25MG
About this Product
SKU:
10-5713
Additional Names:
Lac-Phe|N-lactoyl-phenylalanine
CAS Number:
183241-73-8
Extra Details:
Exercise is associated with transient suppression of appetite which previously has been attributed to induction of appetite-regulatory hormone such as GLP-11 or the increase in circulating metabolites including L-lactate2. A targeted metabolomics approach with blood samples from two independent human exercise studies resulted in the identification of N-lactoyl-phenylalanine (Lac-Phe; 183241-73-8) as a highly upregulated circulating metabolite following exercise.3 Lac-Phe was shown, using pharmacological and genetic methods, to be an exercise-inducible metabolite that suppresses feeding and obesity. A single injection of Lac-Phe was demonstrated to reduce food intake by ~50% in diet-induced obese mice. However, Lac-Phe is completely inactive when administered orally.4
Molecular Weight:
237.26
Physical State:
Solid
Purity:
>98%
Purification:
HPLC Purified
Shipping Conditions:
Ambient
Storage Conditions:
-20[o]C
Supplier:
Focus Biomolecules
Type:
Proteins, Peptides, Small Molecules & Other Biomolecules: Small Molecules