10074-G5
Product Sizes
5 mg
£177.00
10-5627-5MG
25 mg
£300.00
10-5627-25MG
About this Product
- SKU:
- 10-5627
- Extra Details:
- Inhibits c-Myc by disrupting c-Myc/Max heterodimer formation and inhibiting its transcriptional activity.1 10074-G5 binds to the c-Myc bHLHZip domain with Kd=2.8 mM.1 It was cytotoxic in C-Myc-overexpressing cell lines (IC50s = 13 to 15 mM) but was not active in vivo due to rapid metabolism.2 10074-G5 is a useful tool to probe for involvement of c-Myc involvement in cellular processes.3,4 Binds to and sequesters the intrinsically disordered amyloid-B Beta (AB Beta) in its monomeric soluble state and rescues a C. elegans model of AB Beta-associated toxicity.5
- Molecular Weight:
- 332.32
- Physical State:
- Solid
- Purity:
- 98%
- Shipping Conditions:
- Ambient
- Storage Conditions:
- -20[o]C
- Supplier:
- Focus Biomolecules
- Type:
- Proteins, Peptides, Small Molecules & Other Biomolecules: Inhibitors
- Manufacturer's Data Sheet:https://focusbiomolecules.com/new-products/10074-g5-c-myc-inhibitor/