GW788388
Product Sizes
5 mg
£177.00
10-5521-5MG
25 mg
£301.00
10-5521-25MG
About this Product
- SKU:
- 10-5521
- CAS Number:
- 452342-67-5
- Extra Details:
- Potent inhibitor of TGF-B Beta receptor kinases ALK4, ALK5 (IC50=18 nM), ALK7, and TGFB BetaRII, but not BMP type II receptor kinase.1,2 Blocks TGF-B Beta-mediated signaling, including collagen type I and VEGF, in turn reducing fibrosis and angiogenesis in various mouse models.3,4 GW788388 attenuates TGF-B Beta-induced epithelial to mesenchymal transition (EMT) in human peritoneal mesothelial cells.5
- Immunogen:
- Kinase
- Molecular Weight:
- 425.49
- Physical State:
- Solid
- Purity:
- 98%
- Purification:
- HPLC Purified
- Shipping Conditions:
- Ambient
- Storage Conditions:
- -20[o]C
- Supplier:
- Focus Biomolecules
- Type:
- Proteins, Peptides, Small Molecules & Other Biomolecules: Inhibitors
