CDDO-Me
Product Sizes
5 mg
£158.00
10-5449-5MG
25 mg
£241.00
10-5449-25MG
About this Product
- SKU:
- 10-5449
- Additional Names:
- Bardoxolone methyl|CDDO-Methyl ester|RTA 402|TP-155
- CAS Number:
- 218600-53-4
- Extra Details:
- Potent activator of Nrf2 target transcription via interaction with thiol groups of Keap1, an Nrf2 partner, in phase 2 response against oxidative stress.1 Inhibits the NF-K KappaB pathway via inhibition of IKKA Alpha activation in vitro2 and reduces expression of proinflammatory cytokines in vivo3. Alters tumor microenvironment causing breast tumor associated macrophages to switch from tumor-promoting to tumor-inhibiting characteristics in vitro.4 Reduces cancer stem cell marker expression in Ec109 and KYSE70 cells.5
- Immunogen:
- Kinase|Transcription factor
- Molecular Weight:
- 505.7
- Physical State:
- Solid
- Purity:
- >98%
- Purification:
- HPLC Purified
- Shipping Conditions:
- Ambient
- Storage Conditions:
- -20[o]C
- Supplier:
- Focus Biomolecules
- Type:
- Proteins, Peptides, Small Molecules & Other Biomolecules: Small Molecules
