PI-103
Product Sizes
5 mg
£158.00
10-5406-5MG
25 mg
£281.00
10-5406-25MG
About this Product
- SKU:
- 10-5406
- CAS Number:
- 371935-74-9
- Extra Details:
- A potent inhibitor of PI-3 kinase, mTOR and DNA-PK, IC50 = 8, 88, 150, 48, 20, 83 and 2 nM for p110A Alpha, p110B Beta, p110G Gamma, p110D Delta, mTORC1, mTORC2 and DNA-PK respectively.1,2 Synergizes with arsenic disulfide to eradicate AML stem cells by induction of differentiation.3 Inhibits the growth of gefitinib-resistant non-small cell lung cancer cell lines.4 Induces autophagy in drug-resistant glioma.5 Protects against a-synuclein-induced toxicity in human neurons by induction of macroautophagy.6
- Immunogen:
- DNA|Kinase
- Molecular Weight:
- 348.36
- Physical State:
- Solid
- Purity:
- 98%
- Shipping Conditions:
- Ambient
- Storage Conditions:
- -20[o]C
- Supplier:
- Focus Biomolecules
- Type:
- Proteins, Peptides, Small Molecules & Other Biomolecules: Inhibitors
- Sell Sheet 1:
- View Sell Sheet Here
