ABT-869
Product Sizes
5 mg
£153.00
10-5268-5MG
25 mg
£219.00
10-5268-25MG
About this Product
- SKU:
- 10-5268
- Additional Names:
- Linifanib
- CAS Number:
- 796967-16-3
- Extra Details:
- ABT-869 (796967-16-3) ia a structurally novel, potent inhibitor of receptor tyrosine kinases inhibiting VEGFR and PDGFR and related kinases with IC50s= 3, 4, 4, 66, 3 and 14 nM for VEGFR1, VEGFR2, FLT3, PDGFRB Beta, CSF-1R and KIT respectively.1,2 Protects cells from necroptosis and rescues SIRS mice from TNF-A Alpha-induced shock and death.3 Exerts anti-obesity effects by promoting adipocyte browning.4 Inhibits angiogenesis.5
- Immunogen:
- Kinase
- Molecular Weight:
- 375.41
- Physical State:
- Solid
- Purity:
- >98%
- Purification:
- HPLC Purified
- Shipping Conditions:
- Ambient
- Storage Conditions:
- -20[o]C
- Supplier:
- Focus Biomolecules
- Type:
- Proteins, Peptides, Small Molecules & Other Biomolecules: Inhibitors
