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Proteins and Peptides

Phenylhexyl isothiocyanate

Product Sizes
5 mg
£149.00
10-5258-5MG
25 mg
£197.00
10-5258-25MG
About this Product
SKU:
10-5258
Additional Names:
PHI|PHITC
CAS Number:
133920-06-6
Extra Details:
Isothiocyanate constituents of cruciferous vegetables are potent chemopreventive agents for carcinogen-induced cancers in rodents.1 PHITC was the most potent in a series of synthetic arylalkyl isothiocyanates at inhibition of tumorigenicity by NNK, a tobacco-derived nitrosamine, in a mouse model.2 It was also found to induce apoptosis and inhibit leukemia cell growth in vivo3 and was shown to have dual function as a histone deacetylase inhibitor and hypomethylating agent4. PHITC was also shown to restore the activity of mutant p53 and reactivate the p53 pathway in human myeloid leukemia M2 cells.5
Immunogen:
Acetyltransferase|DNA methyltransferase|Protein methyltransferase
Molecular Weight:
219.35
Physical State:
liquid
Purity:
>98%
Shipping Conditions:
Ambient
Storage Conditions:
-20[o]C
Supplier:
Focus Biomolecules
Type:
Proteins, Peptides, Small Molecules & Other Biomolecules: Inhibitors