C-DIM 8
Product Sizes
5 mg
£139.00
10-5157-5MG
25 mg
£195.00
10-5157-25MG
About this Product
- SKU:
- 10-5157
- Additional Names:
- DIM-C-pPhOH
- CAS Number:
- 151358-47-3
- Extra Details:
- C-DIM 8 is an antagonist of the orphan nuclear receptor Nur77 (NR4A1, TR3).1 Induces reactive oxygen species and ER stress in pancreatic cancer cells.2 C-DIM 8 mimics the effect of Nur77 knockdown in non-small-cell lung cancer A549 and H460 cells, inhibiting cell growth and inducing apoptosis which was accompanied by decreased expression of survivin and inhibition of mTORC1 signaling.3 Inhibits the expression of B Beta1- and B Beta3-integrin and blocks integrin-dependent breast cancer cell migration.4 Decreases expression of the histone methyltransferase G9A (EHMT2) in a variety of cancer cell lines.5
- Immunogen:
- ER/Golgi|Protein methyltransferase|Transcription factor
- Molecular Weight:
- 338.41
- Physical State:
- Solid
- Purity:
- 98%
- Shipping Conditions:
- Ambient
- Storage Conditions:
- -20[o]C
- Supplier:
- Focus Biomolecules
- Type:
- Proteins, Peptides, Small Molecules & Other Biomolecules: Inhibitors
