Lopinavir
Product Sizes
25 mg
£139.00
10-5063-25MG
100 mg
£206.00
10-5063-100MG
About this Product
- SKU:
- 10-5063
- Additional Names:
- A-157378|ABT-378
- CAS Number:
- 192725-17-0
- Extra Details:
- Lopinavir (192725-17-0) is a potent and selective inhibitor of HIV-1 protease (IC50 = 6.5 nM, HIV cultured in peripheral blood mononuclear cells; Ki = 1.3 pM) which is highly selective over mammalian proteases.1 Lopinavir suffers from poor bioavailability due to extensive cytochrome P450-mediated metabolism. Thus, combination with ritonavir suppresses metabolism and is a preferred regimen for treatment of HIV infection.2 Inhibits replication of SARS CoV-2 virus in vitro, IC50 = 26.63 uM.3
- Immunogen:
- Protease
- Molecular Weight:
- 628.81
- Physical State:
- Solid
- Purity:
- >98%
- Purification:
- HPLC Purified
- Shipping Conditions:
- Ambient
- Storage Conditions:
- -20[o]C
- Supplier:
- Focus Biomolecules
- Type:
- Proteins, Peptides, Small Molecules & Other Biomolecules: Inhibitors
