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Product Sizes
5 mg
£168.00
10-4919-5MG
25 mg
£281.00
10-4919-25MG
About this Product
SKU:
10-4919
CAS Number:
1357471-57-8
Extra Details:
TJ-M2010-5 is an inhibitor of the toll-like receptor(TLR)/adaptor molecule myeloid differentiation factor 88 (MyD88) signaling pathway, crucial for inflammation and associated with the development of many inflammation-related cancers.1 It ameliorates ischemia-reperfusion injury in various organ models including brain2, liver3, and heart4. TJ-M2010-5 also suppressed proliferation, migration, and invasion in MCF-7 and MDA-MB-231 breast cancer cells.5 It prevented colitis-associated colorectal cancer by impairing myeloid-derived suppressor cells.6
Immunogen:
TLR (Toll-like receptor)
Molecular Weight:
406.55
Physical State:
Solid
Purity:
>98%
Purification:
HPLC Purified
Shipping Conditions:
Ambient
Storage Conditions:
-20[o]C
Supplier:
Focus Biomolecules
Type:
Proteins, Peptides, Small Molecules & Other Biomolecules: Inhibitors