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Product Sizes
5 mg
£149.00
10-4870-5MG
25 mg
£238.00
10-4870-25MG
About this Product
SKU:
10-4870
CAS Number:
1620401-82-2
Extra Details:
UNC0379 is an inhibitor of the lysine methyltransferase SETD8 with selectivity over 15 other methyltransferases.1 IC50's = 7.3 uM in a radioactive methyl transfer assay and 9.0 uM in an MCE assay. UNC0379 treatment of SY5Y and NGP neuroblastoma cell lines lead to activation of p53 and decreased tumor growth in an ex-vivo tumorigenicity assay.2
Immunogen:
Protein methyltransferase
Molecular Weight:
413.56
Physical State:
Solid
Purity:
98%
Shipping Conditions:
Ambient
Storage Conditions:
-20[o]C
Supplier:
Focus Biomolecules
Type:
Proteins, Peptides, Small Molecules & Other Biomolecules: Inhibitors
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