FB23-2
Product Sizes
5 mg
£158.00
10-4852-5MG
25 mg
£281.00
10-4852-25MG
About this Product
- SKU:
- 10-4852
- CAS Number:
- 2243736-45-8
- Extra Details:
- FB23-2 is an inhibitor (IC50 = 2.6 uM) of the mRNA m6A demethylase fat-mass- and obesity-associated protein (FTO).1 Displays significant anti-proliferative activity in NB4 (IC50 = 0.8 uM) and MONOMAC6 (IC50 = 1.5 uM) cells. Selective against the RNA demethylase ALKB5. FB23-2 induced myeloid differentiation and apoptosis in acute myeloid leukemia cells. FB23-2 suppressed the proliferation and migration of hepatocellular carcinoma cells via suppressing the expression of the kinase ERBB3 and human tubulin beta class Iva (TUBB4A).2
- Immunogen:
- Nucleic acid methylation|RNA
- Molecular Weight:
- 392.24
- Physical State:
- Solid
- Purity:
- 98%
- Purification:
- HPLC Purified
- Shipping Conditions:
- Ambient
- Storage Conditions:
- -20[o]C
- Supplier:
- Focus Biomolecules
- Type:
- Proteins, Peptides, Small Molecules & Other Biomolecules: Inhibitors
- Sell Sheet 1:
- View Sell Sheet Here
- Sell Sheet 2:
- View Sell Sheet Here
