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Product Sizes
10 mg
£177.00
10-4850-10MG
50 mg
£315.00
10-4850-50MG
About this Product
SKU:
10-4850
CAS Number:
2375421-09-1
Extra Details:
Cell permeable and exceptionally selective STING agonist (IC50 = 7.8 uM). It displayed robust antitumor activity in B16.F10 melanoma and MC38 colorectal adenocarcinoma mouse models. SR-717 promoted the activation of CD8+ T, natural killer, and dendritic cells as well as promoting antigen cross-priming. It was able to induce PD-L1 expression in THP1 cells and in primary human PBMC's.
Immunogen:
STING
Molecular Weight:
381.27
Physical State:
Solid
Purity:
>98%
Purification:
HPLC Purified
Shipping Conditions:
Ambient
Storage Conditions:
-20[o]C
Supplier:
Focus Biomolecules
Type:
Proteins, Peptides, Small Molecules & Other Biomolecules: Small Molecules
Sell Sheet 1:
View Sell Sheet Here