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Product Sizes
5 mg
£216.00
10-4849-5MG
25 mg
£460.00
10-4849-25MG
About this Product
SKU:
10-4849
CAS Number:
2756566-45-5
Extra Details:
UZH2 (2756566-45-5) is a potent (IC50 = 5 nM) and selective (against METTL1 and METTL16) inhibitor of the RNA methyltransferase METTL3, a key component of the writer complex targeting N6-methyladenosine (m6A), the most common RNA modification. It was able to impair cell growth (GI50 = 12 uM) in MOLM-13 cancer cells (AML).
Immunogen:
Methyltransferase|Nucleic acid methylation|RNA
Molecular Weight:
513.64
Physical State:
Solid
Purity:
>98%
Purification:
HPLC Purified
Shipping Conditions:
Ambient
Storage Conditions:
-20[o]C
Supplier:
Focus Biomolecules
Type:
Proteins, Peptides, Small Molecules & Other Biomolecules: Inhibitors
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