Larotrectinib
Product Sizes
5 mg
£158.00
10-4832-5MG
25 mg
£267.00
10-4832-25MG
About this Product
- SKU:
- 10-4832
- Additional Names:
- ARRY-470|LOXO-101
- CAS Number:
- 1223403-58-4
- Extra Details:
- Larotrectinib is a potent (IC50's < 11 nM) inhibitor of tropomyosin receptor kinases A, B, and C (TrkA, B, and C).1 It is >100 fold selective against a panel of 229 kinases. Larotrectinib markedly attenuated bone cancer pain and significantly blocked the formation of neuroma-like structures and the sprouting of sensory nerve fibers. Larotrectinib caused substantial tumor regression in various cancers displaying TRK gene fusions.2-4 Larotrectinib is the first tissue agnostic drug approved by the FDA.
- Immunogen:
- Cytoskeleton|Kinase
- Molecular Weight:
- 428.44
- Physical State:
- Solid
- Purity:
- 98%
- Purification:
- HPLC Purified
- Shipping Conditions:
- Ambient
- Storage Conditions:
- RT
- Supplier:
- Focus Biomolecules
- Type:
- Proteins, Peptides, Small Molecules & Other Biomolecules: Inhibitors
