WP1066
Product Sizes
10 mg
£177.00
10-4831-10MG
50 mg
£334.00
10-4831-50MG
About this Product
- SKU:
- 10-4831
- CAS Number:
- 857064-38-1
- Extra Details:
- WP1066 (857064-38-1) is an inhibitor of the JAK2/STAT3 pathway as well as STAT5 and AKT.1,2,3 It downregulated Bcl-XL, Mcl-1, and c-myc while activating Bax and inducing apoptosis.1 Active against human malignant glioma U87-MG (IC50 = 5.6uM) and U373-MG (IC50 = 3.7uM) cells. Enhances T-cell cytotoxicity via inhibition of regulatory T-cells.4,5 WP1066 abrogated PD-L1 expression in lymphoma cell lines.6
- Immunogen:
- Kinase|Transcription factor
- Molecular Weight:
- 356.22
- Physical State:
- Solid
- Purity:
- 98%
- Purification:
- HPLC Purified
- Shipping Conditions:
- Ambient
- Storage Conditions:
- -20[o]C
- Supplier:
- Focus Biomolecules
- Type:
- Proteins, Peptides, Small Molecules & Other Biomolecules: Inhibitors
- Sell Sheet 1:
- View Sell Sheet Here
