IPA-3
Product Sizes
10 mg
£163.00
10-4765-10MG
50 mg
£281.00
10-4765-50MG
About this Product
- SKU:
- 10-4765
- CAS Number:
- 42521-82-4
- Extra Details:
- IPA-3 is a selective allosteric inhibitor of Group 1 p21-activated kinase (PAK1 IC50 = 2.5 uM)1 via covalent binding to the PAK1 regulatory domain preventing binding to the upstream activator Cdc422. IPA-3 has been shown to induce cell death in human leukemic cell lines3, significantly inhibit TGFB Beta1-induced prostate cell epithelial to mesenchymal transition4 and inhibits the growth of liver cancer cells5.
- Immunogen:
- Kinase
- Molecular Weight:
- 350.45
- Physical State:
- Solid
- Purity:
- 98%
- Shipping Conditions:
- Ambient
- Storage Conditions:
- -20[o]C
- Supplier:
- Focus Biomolecules
- Type:
- Proteins, Peptides, Small Molecules & Other Biomolecules: Inhibitors
