Skip to content

Basket

You currently have no items in your basket.

Total (excl. vat) £0.00
View basket & checkout
Proteins and Peptides
Product Sizes
5 mg
£158.00
10-4764-5MG
25 mg
£277.00
10-4764-25MG
About this Product
SKU:
10-4764
Additional Names:
DM-3189
CAS Number:
1435934-00-1
Extra Details:
LDN-193189 2HCl is a potent and selective inhibitor of ALK2 (IC50 = 5 nM) and ALK3 (IC50 = 30 nM), thereby inhibiting SMAD1/5/8 phosphorylation.1 Only weak inhibition of ALK4, ALK5, and ALK7 is observed. Promotes neuronal differentiation of human pluripotent stem cells.2-3 LDN-193189 HCl has also been used to examine the role of osteogenesis in prostate tumor metastases in bone.4
Immunogen:
Kinase
Molecular Weight:
479.4
Physical State:
Solid
Purity:
99%
Purification:
HPLC Purified
Shipping Conditions:
Ambient
Storage Conditions:
-20[o]C
Supplier:
Focus Biomolecules
Type:
Proteins, Peptides, Small Molecules & Other Biomolecules: Inhibitors
Sell Sheet 1:
View Sell Sheet Here
Sell Sheet 2:
View Sell Sheet Here