Palbociclib
Product Sizes
5 mg
£149.00
10-4760-5MG
25 mg
£195.00
10-4760-25MG
About this Product
- SKU:
- 10-4760
- Additional Names:
- PD-332991|PD0332991
- CAS Number:
- 571190-30-2
- Extra Details:
- Potent and selective inhibitor of Cdk4, IC50 = 11 nM and Cdk6, IC50 = 16 nM.1 Inhibits phosphorylation of Rb protein and cell cycle progression through G1 in primary 5T33MM cells and sensitized these cells to killing by a proteasome inhibitor (bortezomib) in mouse models.2 Induces autophagy and senescence in AGS gastric cancer cells.3 Clinically useful breast cancer agent.4 Cell cycle inhibitors boost tumor immunogenicity.5
- Immunogen:
- Kinase
- Molecular Weight:
- 447.53
- Physical State:
- Solid
- Purity:
- 99%
- Shipping Conditions:
- Ambient
- Storage Conditions:
- -20[o]C
- Supplier:
- Focus Biomolecules
- Type:
- Proteins, Peptides, Small Molecules & Other Biomolecules: Inhibitors
- Sell Sheet 1:
- View Sell Sheet Here
