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Product Sizes
20 mg
£139.00
10-4742-20MG
100 mg
£192.00
10-4742-100MG
About this Product
SKU:
10-4742
CAS Number:
218457-67-1
Extra Details:
Orally active inhibitor of the Notch signaling activation complex (IC50's from 0.9 to 3.9 uM in various cell-based assays), the most downstream level of the Notch signaling pathway. It inhibited the growth of Notch-addicted human T cell acute lymphoblastic leukemia cells as well as other cell lines. CB-103 also inhibited the growth of human breast cancer and leukemia xenografts without the intestinal toxicity associated with G Gamma-secretase Notch inhibitors.
Immunogen:
Transcription factor
Molecular Weight:
242.32
Physical State:
Solid
Purity:
98%
Purification:
HPLC Purified
Shipping Conditions:
Ambient
Storage Conditions:
RT
Supplier:
Focus Biomolecules
Type:
Proteins, Peptides, Small Molecules & Other Biomolecules: Inhibitors