BO-264
Product Sizes
5 mg
£163.00
10-4685-5MG
25 mg
£281.00
10-4685-25MG
About this Product
- SKU:
- 10-4685
- CAS Number:
- 2408648-20-2
- Extra Details:
- BO-264 is a potent (IC50 = 188 nM) inhibitor of transforming acidic coiled-coil 3 (TACC3), an important protein involved in microtubule stability and centrosome integrity.1 TACC3 is frequently upregulated in a broad range of cancers. BO-264 displayed significant anticancer activity in greater than 90% of cell lines in the NCI-60 human cancer cell line panel. Active in vivo in mice injected with JIMT-1 and EMT6 breast cancer cells as well as mouse colon cancer xenografts HCT-116 and CT-26.
- Immunogen:
- Cytoskeleton
- Molecular Weight:
- 353.38
- Physical State:
- Solid
- Purity:
- 99%
- Purification:
- HPLC Purified
- Shipping Conditions:
- Ambient
- Storage Conditions:
- -20[o]C
- Supplier:
- Focus Biomolecules
- Type:
- Proteins, Peptides, Small Molecules & Other Biomolecules: Inhibitors
- Sell Sheet 1:
- View Sell Sheet Here
