R428
Product Sizes
5 mg
£163.00
10-4676-5MG
25 mg
£281.00
10-4676-25MG
About this Product
- SKU:
- 10-4676
- Additional Names:
- Bemcentinib|BGB324
- CAS Number:
- 1037624-75-1
- Extra Details:
- R428 (1037624-75-1) is a potent and selective inhibitor of AXL kinase (IC50 = 1.4nM).1 R428 has been shown to overcome chemotherapy resistance to various agents in multiple cancer models.2-5 AXL has been shown to suppress myeloid cell activation and function - combined AXL inhibition with R428 and PD-1 blockade showed potent synergistic antitumor effects.6,7
- Immunogen:
- Kinase
- Molecular Weight:
- 506.64
- Physical State:
- Solid
- Purity:
- 98%
- Purification:
- HPLC Purified
- Shipping Conditions:
- Ambient
- Storage Conditions:
- -20[o]C
- Supplier:
- Focus Biomolecules
- Type:
- Proteins, Peptides, Small Molecules & Other Biomolecules: Inhibitors
- Sell Sheet 1:
- View Sell Sheet Here
