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Proteins and Peptides
Product Sizes
10 mg
£139.00
10-4631-10MG
50 mg
£182.00
10-4631-50MG
About this Product
SKU:
10-4631
CAS Number:
88416-50-6
Extra Details:
Clodronate is a first generation non-nitrogenous bisphosphonate drug for the prevention and treatment of osteoporosis and skeletal fractures/hypercalcemia in patients with cancer. It strongly binds to hydroxyapatite and directly reduces osteoclast activity.1 Clodronate is metabolized in vitro to a cytotoxic ATP analog (AppCCl2p) which inhibits ADP/ATP translocase in the mitochondrial inner membrane leading to osteoclast apoptosis.2
Molecular Weight:
360.92
Physical State:
Solid
Purity:
98%
Shipping Conditions:
Ambient
Storage Conditions:
-20[o]C
Supplier:
Focus Biomolecules
Type:
Proteins, Peptides, Small Molecules & Other Biomolecules: Small Molecules