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Product Sizes
5 mg
£163.00
10-4628-5MG
25 mg
£281.00
10-4628-25MG
About this Product
SKU:
10-4628
Additional Names:
SIRT 1933
CAS Number:
1001645-58-4
Extra Details:
SIRT1 activator (EC1.5 = 0.16 uM, max activation = 781%).1 It reduced glucose levels and hyperinsulinemia in DIO, Lepob/ob mice and Zucker fa/fa rats. SRT1720 enhanced endurance running and protected against diet-induced obesity and insulin resistance via enhancement of oxidative metabolism in skeletal muscle, liver, and brown adipose tissue.2 It induced mitochondrial biogenesis in oxidant-induced renal proximal tube cell injury.3 SRT1720 repressed circadian clock gene expression and decreased H3 K9/K14 acetylation in a time-specific manner.4 It attenuated angiotensin II-induced atherosclerosis by inhibiting the vascular inflammatory response.5
Immunogen:
Protein deacetylase
Molecular Weight:
506.02
Physical State:
Solid
Purity:
98%
Purification:
HPLC Purified
Shipping Conditions:
Ambient
Storage Conditions:
-20[o]C
Supplier:
Focus Biomolecules
Type:
Proteins, Peptides, Small Molecules & Other Biomolecules: Small Molecules
Sell Sheet 1:
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Sell Sheet 2:
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