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Proteins and Peptides

Fumarate hydratase-IN-1

Product Sizes
5 mg
£168.00
10-4578-5MG
25 mg
£281.00
10-4578-25MG
About this Product
SKU:
10-4578
CAS Number:
1644060-37-6
Extra Details:
Fumarate hydratase-IN-1 is a pro-drug inhibitor of fumarate hydratase, an important enzyme in the tricarboxylic acid (TCA) cycle. This cell permeable compound is converted to the active carboxylic acid by intracellular esterases (Ki = 4.5 uM for free acid). The ethyl ester displayed cell-growth inhibitory activity against several cancer lines under nutrient (glucose) deprived conditions with an average IC50 = 2.2 uM.
Molecular Weight:
446.55
Physical State:
Solid
Purity:
>98%
Purification:
HPLC Purified
Shipping Conditions:
Ambient
Storage Conditions:
-20[o]C
Supplier:
Focus Biomolecules
Type:
Proteins, Peptides, Small Molecules & Other Biomolecules: Inhibitors