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Product Sizes
50 mg
£134.00
10-4569-50MG
250 mg
£168.00
10-4569-250MG
About this Product
SKU:
10-4569
CAS Number:
110117-83-4
Extra Details:
Indoximod is a modulator of indoleamine 2,3-dioxygenase (IDO) activity.1 IDO can be used by tumors to avoid elimination by the host immune response2,3, thus inhibition of IDO is an interesting cancer therapeutic option. Indoximod is not a direct inhibitor of IDO, but instead targets the IDO gene leading to downstream effects.3 IDO-mediated catabolism of tryptophan inhibits the immunoregulatory kinases mTOR and PKC5. This is relieved by Indoximod acting as a potent tryptophan mimetic restoring mTOR and PKC signaling.4
Immunogen:
Tryptophan
Molecular Weight:
218.25
Physical State:
Solid
Purity:
>98%
Shipping Conditions:
Ambient
Storage Conditions:
-20[o]C
Supplier:
Focus Biomolecules
Type:
Proteins, Peptides, Small Molecules & Other Biomolecules: Small Molecules