NLG919
Product Sizes
5 mg
£158.00
10-4564-5MG
25 mg
£267.00
10-4564-25MG
About this Product
- SKU:
- 10-4564
- CAS Number:
- 1402836-58-1
- Extra Details:
- NLG919 (1402836-58-1) is a potent IDO-pathway inhibitor (Ki = 7nM; EC50 = 75nM).1 It synergizes with chemo-radiation therapy to promote T cell dependent complement deposition in a murine model of glioblastoma.2 In combination with paclitaxel in a mouse B16-F10 melanoma model, NLG919 increased the percentage of CD3+, CD8+, and CD4+ T cells and secretion of IFN-G Gamma and interleukin-2 while decreasing the percentage of CD4+CD25+ regulatory T cells.3
- Immunogen:
- Tryptophan
- Molecular Weight:
- 282.39
- Physical State:
- Solid
- Shipping Conditions:
- Ambient
- Storage Conditions:
- -20[o]C
- Supplier:
- Focus Biomolecules
- Type:
- Proteins, Peptides, Small Molecules & Other Biomolecules: Inhibitors
