NHI-2
Product Sizes
10 mg
£220.00
10-4555-10MG
50 mg
£541.00
10-4555-50MG
About this Product
- SKU:
- 10-4555
- Extra Details:
- NHI-2 is a selective inhibitor of Lactate Dehydrogenase A (LDHA) - IC50 in vitro = 14.7 uM (NADH), 10.5 uM (Pyruvate).1 NHI-2 has also shown cellular growth inhibitory effects against pancreatic cancer cells (PANC-1 cells IC50 = 22.2 uM normoxic and 4.0 uM hypoxic; LPC006 cells IC50 = 17.8 uM normoxic and 1.1 uM hypoxic) with increased efficacy in a cancer cells hypoxic environment.2 LDHA is a key enzyme involved in the Warburg effect and a cancer cells ability to survive in a hypoxic environment.
- Molecular Weight:
- 335.28
- Physical State:
- Solid
- Purity:
- 98%
- Purification:
- HPLC Purified
- Shipping Conditions:
- Ambient
- Storage Conditions:
- -20[o]C
- Supplier:
- Focus Biomolecules
- Type:
- Proteins, Peptides, Small Molecules & Other Biomolecules: Inhibitors
- Manufacturer's Data Sheet:https://focusbiomolecules.com/cellular-metabolism/nhi-2-ldha-inhibitor/