SAG
Product Sizes
1 mg
£134.00
10-4525-1MG
5 mg
£192.00
10-4525-5MG
About this Product
- SKU:
- 10-4525
- Additional Names:
- Smoothened Agonist
- CAS Number:
- 364590-63-6
- Extra Details:
- Smoothened agonist which bind directly to SMO and can block SMO inhibition by cyclopamine. The conformation of SMO is altered by SAG binding which results in the accumulation of SMO in cilia and activated gene transcription. It should be noted that SAG inhibits hedgehog signaling at concentrations greater than 1 uM (EC50 for SMO activation is ~ 3 nM).1
- Immunogen:
- GPCR
- Molecular Weight:
- 490.07
- Physical State:
- Solid
- Purity:
- >98%
- Purification:
- HPLC Purified
- Shipping Conditions:
- Ambient
- Storage Conditions:
- -20[o]C
- Supplier:
- Focus Biomolecules
- Type:
- Proteins, Peptides, Small Molecules & Other Biomolecules: Small Molecules
- Sell Sheet 1:
- View Sell Sheet Here
- Sell Sheet 2:
- View Sell Sheet Here
