Ruxolitinib
Product Sizes
5 mg
£163.00
10-4511-5MG
10 mM (in 1 ml DMSO)
£163.00
10-4511-10MM(IN1MLDMSO)
25 mg
£195.00
10-4511-25MG
About this Product
- SKU:
- 10-4511
- Additional Names:
- INCB 018424
- CAS Number:
- 941678-49-5
- Extra Details:
- Potent and selective JAK1&2 inhibitor, IC50s=2.7, 4.5 and 322 nM forJAK1, JAK2 and JAK3 respectively.1 Blocks IL-6 signaling (IC50=281 nM) and proliferation of JAK2V617F+ Ba/F3 cells (IC50=127 nM).2 Inhibits the proinflammatory secretome of senescent cells.3 The JAK1 S646P mutant is highly sensitive to ruxolitinib.4 Clinically useful cancer chemotherapeutic.
- Immunogen:
- Kinase
- Molecular Weight:
- 306.37
- Physical State:
- Solid
- Purity:
- 99%
- Purification:
- HPLC Purified
- Shipping Conditions:
- Ambient
- Storage Conditions:
- -20[o]C
- Supplier:
- Focus Biomolecules
- Type:
- Proteins, Peptides, Small Molecules & Other Biomolecules: Inhibitors
