SLB1122168
Product Sizes
25 mg
£402.00
10-4396-25MG
5 mg
£402.00
10-4396-5MG
About this Product
- SKU:
- 10-4396
- CAS Number:
- 2999629-17-1
- Extra Details:
- SLB1122168 is a potent (IC50 = 94 nM) second generation sphingosine-1-phosphate transporter Spinster Homolog 2 (Spns2) inhibitor. In vivo, it significantly reduced circulating lymphocyte counts but did not reduce plasma sphigosine-1-phosphate levels as with the first generation inhibitor SLF1081851 (Focus Cat# 10-4395). Spns2 inhibitors represent potential alternative immunomodulatory agents to S1P receptor agonists as they are able in induce lymphopenia without drastic changes to systemic S1P levels or stimulating the S1P1-5 signaling pathway.
- Molecular Weight:
- 394
- Physical State:
- Solid
- Purity:
- >98%
- Purification:
- HPLC Purified
- Shipping Conditions:
- Ambient
- Storage Conditions:
- -20[o]C
- Supplier:
- Focus Biomolecules
- Type:
- Proteins, Peptides, Small Molecules & Other Biomolecules: Inhibitors
