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Product Sizes
10 mg
£163.00
10-4380-10MG
50 mg
£286.00
10-4380-50MG
About this Product
SKU:
10-4380
Additional Names:
AG 3-5
CAS Number:
36945-98-9
Extra Details:
Icilin is an agonist of cold-sensitive TRP channels with 2.5-fold greater efficacy and 200-fold greater potency than menthol (EC50 = 0.36 uM for CRM1, rat orthologue of TRPM8).1 Agonist at TRPM8 (EC50 = 0.2 uM)2 and ANKTM1(TRPA1)3. Agonist effects require Ca2+ and are pH dependent.2,4 Icilin induced G1 arrest in PC-3 prostate cancer cells without cell death.5
Immunogen:
Ion channel
Molecular Weight:
311.29
Physical State:
Solid
Purity:
>98%
Shipping Conditions:
Ambient
Storage Conditions:
-20[o]C
Supplier:
Focus Biomolecules
Type:
Proteins, Peptides, Small Molecules & Other Biomolecules: Small Molecules
Sell Sheet 1:
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Sell Sheet 2:
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