(R)-GNE-140
Product Sizes
5 mg
£177.00
10-4355-5MG
25 mg
£277.00
10-4355-25MG
About this Product
- SKU:
- 10-4355
- CAS Number:
- 2003234-63-5
- Extra Details:
- (R)-GNE-140 is a potent (IC50's: LDHA = 3 nM, LDHB = 5 nM, LDHC = 5 nM) pan-lactate dehydrogenase inhibitor.1 It significantly decreased lactate levels in vivo, although the effects were transient. GNE-140 suppressed lactic acid production, severely stunted glucose utilization, and impeded the anaerobic glycolytic pathway in MDA-MB-231 triple negative breast cancer cells.2
- Immunogen:
- Dehydrogenase (GAPDH, GPDH, IMPDH, PHGDH, LDH, DHODH, ALDH, GDH, IDH, UGDH, DPD, DHPDH, KGDH, PDH, and MDH)
- Molecular Weight:
- 499.04
- Physical State:
- Solid
- Purity:
- >98%
- Purification:
- HPLC Purified
- Shipping Conditions:
- Ambient
- Storage Conditions:
- -20[o]C
- Supplier:
- Focus Biomolecules
- Type:
- Proteins, Peptides, Small Molecules & Other Biomolecules: Inhibitors
