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Product Sizes
5 mg
£187.00
10-4292-5MG
25 mg
£358.00
10-4292-25MG
About this Product
SKU:
10-4292
CAS Number:
2763063-26-7
Extra Details:
NGI-189 is a second generation (NGI-1) oligosaccharyltransferase (OST) inhibitor (IC50 = 90 nM) with preference for OST-A over OST-B. It prevented N-glycosylation of EGFR mutant NSCLC cells and was tolerated in vivo. NGI-189 prevented tumor growth in YU-006 and YU-101 NSCLC tumor xenograft models.
Immunogen:
Glycosylation
Molecular Weight:
478.63
Physical State:
Solid
Purity:
>98%
Purification:
HPLC Purified
Shipping Conditions:
Ambient
Storage Conditions:
-20[o]C
Supplier:
Focus Biomolecules
Type:
Proteins, Peptides, Small Molecules & Other Biomolecules: Inhibitors