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Product Sizes
10 mg
£144.00
10-4290-10MG
50 mg
£202.00
10-4290-50MG
About this Product
SKU:
10-4290
Additional Names:
NSC139021
CAS Number:
1147-56-4
Extra Details:
ERGi-USU selectively inhibits the growth of ERG-positive VCaP prostate cancer cells, COLO320 colon cancer cells, KG-1 and MOLT-4 leukemia cells with minimal effect on ERG-negative cells or normal prostate or endothelial cells (IC50 = 169 nM for cell growth and 315 nM for ERG protein in VCaP cells). It selectively inhibits the kinase RIOK2 (Kd = 200 nM) causing disruption of ribosomal biogenesis and ribosomal stress.
Immunogen:
Kinase|Transcription factor
Molecular Weight:
255.30
Physical State:
Solid
Purity:
98%
Shipping Conditions:
Ambient
Storage Conditions:
-20[o]C
Supplier:
Focus Biomolecules
Type:
Proteins, Peptides, Small Molecules & Other Biomolecules: Inhibitors