WC522
Product Sizes
5 mg
£177.00
10-4241-5MG
25 mg
£320.00
10-4241-25MG
About this Product
- SKU:
- 10-4241
- Extra Details:
- WC522 blocks the cholesterol-dishevelled interaction leading to inhibition of B Beta-catenin signaling. It specifically inhibits the Dvl2-PDZ-cholesterol interaction (IC50 = 40 nM) leading to suppression of both Wnt-independent and Wnt-stimulated B Beta-catenin signaling (IC50 = 150 nM). WC522 inhibits cell proliferation in APC-truncated colorectal carcinoma cells and colorectal carcinoma HCT15 xenografts in mice.
- Immunogen:
- Transcription factor
- Molecular Weight:
- 380.53
- Physical State:
- Amber viscous oil
- Purity:
- >98%
- Purification:
- HPLC Purified
- Shipping Conditions:
- Ambient
- Storage Conditions:
- -20[o]C
- Supplier:
- Focus Biomolecules
- Type:
- Proteins, Peptides, Small Molecules & Other Biomolecules: Inhibitors
