Siramesine
Product Sizes
5 mg
£173.00
10-4202-5MG
25 mg
£301.00
10-4202-25MG
About this Product
- SKU:
- 10-4202
- Additional Names:
- Lu 28-179
- CAS Number:
- 147817-50-3
- Extra Details:
- Siramesine (Lu 28-179) is a 2 selective agonist (IC50's: 1 = 17nM, 2 = 0.2nM).1 It produced non-sedating potent and long-last anxiolytic effects in rodents.2 Siramesine induced caspase-independent programmed cell death in various cancer cell lines via increased levels of ROS and lysosomal leakage.3,4,5 Mitochondrial destabilization via loss of membrane potential and increased ROS has also been offered as a mechanism of action for the triggering of cell death by Siramesine.6
- Immunogen:
- ER/Golgi|Lysosome
- Molecular Weight:
- 454.59
- Physical State:
- Solid
- Purity:
- 98%
- Purification:
- HPLC Purified
- Shipping Conditions:
- Ambient
- Storage Conditions:
- -20[o]C
- Supplier:
- Focus Biomolecules
- Type:
- Proteins, Peptides, Small Molecules & Other Biomolecules: Small Molecules
- Sell Sheet 1:
- View Sell Sheet Here
