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Product Sizes
5 mg
£197.00
10-4082-5MG
25 mg
£411.00
10-4082-25MG
About this Product
SKU:
10-4082
CAS Number:
3091640-25-1
Extra Details:
UNC9435 is a potent dual inhibitor of TYRO3 (IC50 = 3.7 nM) and MERTK (IC50 = 1.1 nM), TAM family kinases with roles in oncogenesis and innate immunity.1 Displays 46-fold selectivity over the TAM kinase AXL and 120-fold selectivity over FLT3. It inhibited colony formation in H1650 and H1975 NSCLC cell lines and inhibited efferocytosis.
Immunogen:
Kinase
Molecular Weight:
520.54
Physical State:
Solid
Purity:
>98%
Purification:
HPLC Purified
Shipping Conditions:
Ambient
Storage Conditions:
-20[o]C
Supplier:
Focus Biomolecules
Type:
Proteins, Peptides, Small Molecules & Other Biomolecules: Inhibitors