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Product Sizes
10 mg
£149.00
10-4075-10MG
50 mg
£238.00
10-4075-50MG
About this Product
SKU:
10-4075
CAS Number:
2410846-16-9
Extra Details:
Separase is a cysteine protease that triggers chromosome segregation during mitosis and is highly overexpressed in many cancers. SIC5-6 is an inhibitor of separase with no inhibition of the related protease caspase-1 in vitro. HeLa cells with dysregulated separase activity showed severe chromosome segregation defects on treatment with 30 uM SIC5-6 indicating a potential attractive new chemotherapeutic target.
Immunogen:
Cytoskeleton|Protease
Molecular Weight:
581.47
Physical State:
Solid
Purity:
97%
Purification:
HPLC Purified
Shipping Conditions:
Ambient
Storage Conditions:
-20[o]C
Supplier:
Focus Biomolecules
Type:
Proteins, Peptides, Small Molecules & Other Biomolecules: Inhibitors