SR1078
Product Sizes
10 mg
£168.00
10-4066-10MG
50 mg
£267.00
10-4066-50MG
About this Product
- SKU:
- 10-4066
- CAS Number:
- 1246525-60-9
- Extra Details:
- Agonist of the orphan nuclear receptors RORA Alpha and RORG Gamma.1 It attenuated intrapancreatic pathological changes in mouse models of chronic pancreatitis via restoration of the circadian stabilizing loop.2 SR1078 stimulation of RORA Alpha restored clock protein BMAL1 expression and oscillation and blocked MYCN-mediated neuroblastoma growth.3 It reduced repetitive behavior is a mouse model of autism suggesting a potential therapeutic pathway for the disorder.4 SR1078 treatment lead to an increase in p53 levels and increased apoptosis in HepG2 cells.5
- Immunogen:
- Retinoid receptor and related|Transcription factor
- Molecular Weight:
- 431.26
- Physical State:
- Solid
- Purity:
- >98%
- Purification:
- HPLC Purified
- Shipping Conditions:
- Ambient
- Storage Conditions:
- -20[o]C
- Supplier:
- Focus Biomolecules
- Type:
- Proteins, Peptides, Small Molecules & Other Biomolecules: Small Molecules
