Skip to content

Basket

You currently have no items in your basket.

Total (excl. vat) £0.000
View basket & checkout
Product Sizes
5 mg
£182.00
10-4063-5MG
25 mg
£359.00
10-4063-25MG
About this Product
SKU:
10-4063
Extra Details:
A-438079 (899431-18-6) is a competitive P2X7 receptor antagonist (pIC50 = 6.9).1 Displayed antinociceptive effects in a rat model of neuropathic pain.2 A-438079 prevented the LPS-induced release of IL-1B Beta and attenuated LPS-induced (via intrathecal lumbar injection) mechanical hyperalgesia in rat hindpaws.3 It prevented mechanical hyperalgesia following peripheral nerve injury.4 A-438079 protected against cerebral ischemia/reperfusion injury in a rat model via reduction of the neuroinflammatory response.5
Molecular Weight:
342.61
Physical State:
Solid
Purity:
98%
Purification:
HPLC Purified
Shipping Conditions:
Ambient
Storage Conditions:
-20[o]C
Supplier:
Focus Biomolecules
Type:
Proteins, Peptides, Small Molecules & Other Biomolecules: Inhibitors