P053
Product Sizes
5 mg
£158.00
10-4060-5MG
25 mg
£253.00
10-4060-25MG
About this Product
- SKU:
- 10-4060
- CAS Number:
- 1022417-69-1
- Extra Details:
- P053 is a selective inhibitor of protein phosphatase 5 (PP5) - IC50 = 706 nM.1 PP5 regulates signaling cascades that are responsible for tumor initiation, progression, and metastasis and is thus an interesting anticancer target. P053 induced apoptosis in 786-O renal carcinoma cells. Inhibition of PP5 by P053 prevents deactivation of the death effector protein FADD and activates the extrinsic apoptosis pathway complex II.
- Immunogen:
- Phosphatase
- Molecular Weight:
- 342.41
- Physical State:
- Solid
- Purity:
- >98%
- Purification:
- HPLC Purified
- Shipping Conditions:
- Ambient
- Storage Conditions:
- -20[o]C
- Supplier:
- Focus Biomolecules
- Type:
- Proteins, Peptides, Small Molecules & Other Biomolecules: Inhibitors
- Sell Sheet 1:
- View Sell Sheet Here
