AZD5904
Product Sizes
5 mg
£177.00
10-4058-5MG
25 mg
£320.00
10-4058-25MG
About this Product
- SKU:
- 10-4058
- Additional Names:
- TX4
- CAS Number:
- 618913-30-7
- Extra Details:
- A mechanism-based inactivator of myeloperoxidase (IC50 = 200 nM), reacting with hydrogen peroxide in neutrophils to inactivate the enzyme.1 This prevents production of hypochlorous acid and concomitant oxidative stress. Importantly, neutrophil bactericidal activity was slowed but not stopped. AZD5904 did not inactivate thyroid peroxidase or lactoperoxidase. AZD5904 prevented the onset and reversed established high-fat diet induced microvascular insulin resistance.2 It also alleviated the relaxation defect in hypertrophic induced pluripotent cardiomyocytes via restoration of MYBPC3 phosphorylation, suggesting potential therapeutic value in treating hypertrophic cardiomyopathy.3
- Immunogen:
- Glutathione
- Molecular Weight:
- 252.29
- Physical State:
- Solid
- Purity:
- >98%
- Shipping Conditions:
- Ambient
- Storage Conditions:
- -20[o]C
- Supplier:
- Focus Biomolecules
- Type:
- Proteins, Peptides, Small Molecules & Other Biomolecules: Inhibitors
