GSK484 hydrochloride
Product Sizes
5 mg
£187.00
10-4043-5MG
25 mg
£363.00
10-4043-25MG
About this Product
- SKU:
- 10-4043
- CAS Number:
- 1652591-81-5
- Extra Details:
- GSK484 is a potent (IC50 = 50 nM) and selective inhibitor of protein arginine deiminase (PAD4).1 It blocks neutrophil extracellular trap formation in human neutrophils.1,2 GSK484 abrogates thrombus formation on heparin-induced thrombocytopenia/thrombosis.3 It protected against reperfusion injury in both stroke4 and cardiac5 models. GSK484 attenuated tumor cell stemness in esophageal squamous cell carcinoma.6 It prevented surgery-induced tumor recurrence via inhibition of neutrophil extracellular trap-induced reprogramming of cancer cell metabolism.7
- Molecular Weight:
- 510.04
- Physical State:
- Solid
- Purity:
- >98%
- Purification:
- HPLC Purified
- Shipping Conditions:
- Ambient
- Storage Conditions:
- -20[o]C
- Supplier:
- Focus Biomolecules
- Type:
- Proteins, Peptides, Small Molecules & Other Biomolecules: Inhibitors
